Cormac T Taylor Selected Research

oxalylglycine

1/2020	Prolyl Hydroxylase Inhibition Mitigates Pouchitis.
1/2019	Hypoxia-inducible factor hydroxylase inhibition enhances the protective effects of cyclosporine in colitis.
1/2019	Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes.
12/2016	Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].
11/2015	Targeted delivery of the hydroxylase inhibitor DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis.
1/2008	The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.

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Cormac T Taylor Research Topics

Disease

85	Hypoxia (Hypoxemia) 01/2022 - 01/2002
30	Inflammation (Inflammations) 01/2022 - 08/2004
13	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 12/2007
9	Colitis 01/2019 - 12/2007
9	Neoplasms (Cancer) 01/2018 - 12/2004
6	Reperfusion Injury 07/2012 - 06/2002
4	Infections 01/2020 - 09/2011
4	Ischemia 07/2012 - 08/2003
3	Fibrosis (Cirrhosis) 12/2016 - 07/2007
2	Chronic Renal Insufficiency 01/2022 - 01/2019
2	Ulcerative Colitis 01/2020 - 11/2015
2	Anemia 01/2019 - 01/2018
2	Disease Progression 01/2019 - 03/2014
2	Hypercapnia 05/2016 - 04/2012
2	Acute Kidney Injury (Acute Renal Failure) 08/2003 - 06/2002
1	Iron Deficiencies 01/2022
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021
1	Sepsis (Septicemia) 01/2021
1	Neuroblastoma 11/2020
1	Pouchitis 01/2020
1	Herpes Zoster 01/2020
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2020
1	Edema (Dropsy) 01/2019
1	Allergic Contact Dermatitis 01/2019
1	Kidney Diseases (Kidney Disease) 01/2018
1	Infertility (Sterility) 05/2017
1	Pneumonia (Pneumonitis) 01/2017
1	Trypanosomiasis 11/2016
1	Respiratory Tract Diseases (Respiratory Tract Disease) 05/2016
1	Communicable Diseases (Infectious Diseases) 03/2014

Drug/Important Bio-Agent (IBA)

41	Oxygen (Dioxygen)IBA 01/2022 - 12/2003
28	Transcription Factors (Transcription Factor)IBA 01/2022 - 12/2003
23	Mixed Function Oxygenases (Monooxygenases)IBA 01/2022 - 01/2008
14	EnzymesIBA 01/2020 - 05/2010
12	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2020 - 12/2003
12	NF-kappa B (NF-kB)IBA 01/2016 - 10/2006
9	Proteins (Proteins, Gene)FDA Link 11/2020 - 10/2010
6	CytokinesIBA 01/2021 - 06/2002
6	oxalylglycineIBA 01/2020 - 01/2008
6	Messenger RNA (mRNA)IBA 12/2015 - 08/2003
5	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 07/2007
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 02/2003
4	Prolyl-Hydroxylase InhibitorsIBA 01/2019 - 11/2006
4	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2010 - 12/2004
3	CollagenIBA 01/2021 - 12/2016
3	Phenobarbital (Luminal)FDA Link 01/2019 - 12/2007
3	LuciferasesIBA 01/2018 - 01/2011
3	Protein Isoforms (Isoforms)IBA 01/2018 - 10/2006
3	Dextrans (Dextran)FDA Link 12/2016 - 01/2008
3	ElementsIBA 01/2016 - 12/2004
3	Small Interfering RNA (siRNA)IBA 07/2007 - 02/2005
3	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 10/2006 - 02/2003
2	LipopolysaccharidesIBA 01/2021 - 01/2006
2	CaspasesIBA 11/2020 - 04/2005
2	Dextran SulfateIBA 01/2020 - 01/2019
2	AntigensIBA 01/2019 - 12/2007
2	Pharmaceutical PreparationsIBA 01/2019 - 11/2015
2	ChemokinesIBA 01/2019 - 06/2002
2	AsparagineIBA 01/2018 - 01/2016
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 12/2016 - 01/2008
2	RE1-silencing transcription factorIBA 01/2016 - 12/2015
2	UbiquitinIBA 02/2011 - 02/2003
2	Adenosine Triphosphate (ATP)IBA 02/2011 - 01/2008
2	Proline (L-Proline)FDA Link 10/2010 - 11/2006
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2010 - 12/2003
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2007 - 08/2003
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2005 - 10/2003
2	LipoxinsIBA 08/2003 - 06/2002
1	Transferrin (beta 2 Transferrin)IBA 01/2022
1	C-Reactive ProteinIBA 01/2022
1	Erythropoietin FDA Link 01/2022
1	Ferritins (Ferritin)IBA 01/2022
1	IronIBA 01/2022
1	Extracellular Matrix ProteinsIBA 01/2021
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2021
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2020
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2020
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 11/2020
1	Tight Junction ProteinsIBA 01/2020
1	polypentamethylenehexamethylenedicarbamateIBA 01/2020
1	Claudin-1IBA 01/2020
1	DinitrofluorobenzeneIBA 01/2019
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2019
1	Virulence Factors (Pathogenicity Factors)IBA 01/2017
1	Carbon DioxideIBA 05/2016
1	Proton-Translocating ATPases (ATPase, H+)IBA 05/2016
1	bafilomycin A1IBA 05/2016
1	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2016
1	Deubiquitinating EnzymesIBA 01/2016
1	Carrier Proteins (Binding Protein)IBA 01/2016
1	ubiquitin-aldehydeIBA 01/2016
1	Butyrates (Butyrate)IBA 05/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2015
1	paricalcitol (Zemplar)FDA Link 01/2015
1	rho-Associated KinasesIBA 01/2013
1	Glycogen Synthase KinasesIBA 04/2012
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 04/2012

Therapy/Procedure

8	Therapeutics 01/2022 - 05/2010
1	Ligation 01/2021
1	Restorative Proctocolectomy 01/2020